Give Them Their Run Back
KHP-1 is a single-injection regenerative gene therapy in development to treat osteoarthritis in dogs.
Real Dogs. Real Transformations.
See the difference KHP-1 can make — before and after treatment.
Osteoarthritis Is a Bigger Problem Than Most Pet Parents Realize
It’s one of the leading causes of chronic pain in aging dogs — and one of the most under-treated.
89M
pet dogs in the US
1 in 5
adult dogs show clinical signs of OA
~80%
of dogs over age eight are affected
0
disease-modifying therapies approved today
How KHP-1 Works

1. Diagnosis & Consultation
Your veterinarian evaluates your dog’s joints and confirms candidacy for treatment.

2. Single In-Clinic Injection
A quick, single injection delivered directly to the affected joint — most dogs are in and out the same day.

3. Renewed Mobility
Within weeks, pet owners can see their dogs moving more comfortably, regaining mobility, and enjoying a better quality of life.
Real Dogs Have Already Been Treated
Client-owned dogs with naturally occurring OA, treated at SpotOn Veterinary Hospital, CT.
DOZENS
of dogs treated to date
5 yrs
longest follow-up after one dose
0
drug-related adverse events observed
1
injection — no re-dosing
“After years of watching him struggle to get up, seeing him run again felt like a miracle.”
— Benjamin’s pet parent
Owner- and vet-reported gains in mobility and pain were observed in this early pilot. Controlled efficacy will be established in an upcoming registrational study.
Is KHP-1 Right for Your Dog?
Learn about the science behind KHP-1, or reach out to our team with your questions.
